Neuroplasticity is what makes it possible to recover and improve updating and other cognitive skills.Cogni Fit has a battery of clinical exercises designed to help recover updating and other cognitive deficits.To date, the field has lacked a simple behavioral paradigm that can measure whether original and updated information is remembered in a single test session.To address this gap, we have developed a novel memory updating paradigm, called the Objects in Updated Locations (OUL) task that is capable of assessing memory updating in a non-stressful task that is appropriate for both young and old rodents.
Finally, using OUL, we show that memory updating is impaired in aging, 18-m.o. Together, these results demonstrate that hippocampal memory updating is impaired with aging and establish that the OUL paradigm is an effective, sensitive method of assessing memory updating in rodents. John Guzowski for his assistance analyzing and interpreting cat FISH data and Drs.
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The present study investigated the relative influence of three understudied attention mechanisms on the verbal working memory span of school-age children: memory updating; attention focus switching; and sustained attention.
Jennifer Czerniawski, and Terra White for their technical support in conducting the cat FISH experiments. Adeela Syed and the UC Irvine Optical Biology Center (OBC) for training and assistance collecting the confocal images.
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